16-Year-Old Indian Origin Boy Finds a Way to Make a Deadly Form of Breast Cancer More Treatable

Krtin Nithiyandam, a 16-year-old boy of Indian origin in the UK, claims to have found a way to make a lethal form of breast cancer more treatable. It is called the triple negative breast cancer and it is considered deadly because it does not respond to drugs. It is a kind breast cancer that shows aggressive tumour behaviour and poor prognosis. Usually, hormones like oestrogen and progesterone drive many forms of breast cancer. They get attached to the hormone receptors in the cancer cells and contribute to their growth. These receptors are basically proteins found in and on breast cells and they receive messages from hormones telling the cells to grow. When drugs such as tamoxifen are used during treatment, they block those hormones and inhibit growth of the disease. But such drugs are ineffective on triple negative breast cancer because these cancer cells don't have any receptors. An exhausting combination of surgery, radiation and chemotherapy is required to eliminate this kind of cancer, which in turn reduce the chances of survival.

Krtin told The Telegraph, adding that he has found a way to silence the genes that produce ID4. He also discovered that chemotherapy is more effective when the activity of a tumour suppressor called Phosphatase and tensin homolog (PTEN) is increased. And that a combination of these treatments could be more successful than the traditional cure, which uses several drugs. This therapy treatment idea was shortlisted for The Big Bang Fair programme that recognises various young scientists across the UK for their ground-breaking research. This is not the first time that Krtin is receiving international recognition for his research in the field of medical science. Last year, he won a grand prize at the Google Science Fair for his test that might spot Alzheimer’s 10 years before it is diagnosed.

"Where There Is A Will There Is A Way".


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